Endocrine Abstracts

Blood-borne bacteria, fungi and viral agents can activate cells of the innate immune system by interacting with pattern-recognition or Toll receptors on the surface of immune cells. We demonstrate here that mRNA for Toll receptors is ubiquitously expressed in a range of transformed and normal cell types. These findings raise the possibility that infection could induce an inflammatory response in somatic tissues and this might i), provide a milieu for changes in normal cells th...

Many evidences have shown that the beneficial effect of statins on the cardiovascular disease may be not only due to their cholesterol-lowering, but also may result from their non-lipid related effects, such as the improvement of endothelial function, the inhibition of smooth muscle proliferation, etc\. Here we investigated the effect of fluvastatin on H2O2-induced oxidative cell damage and the underlying mechanism in human umbilical vein endothelial cell...